FABP4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFABP4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionFatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). The predominant fatty acid binding protein found in adipocytes is FABP4, also called adipocyte fatty acid binding protein or aP2. FABP4 is also expressed in macrophages (3). FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes (4). Mice deficient in both FABP4 and ApoE show protection against atherosclerosis when compared with mice deficient only in ApoE (3).
ImmunogenImmunogen: Recombinant protein of human FABP4 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[FABP4; aP2; ALBP; Fatty acid binding protein 4; AFABP; A FABP]
Gene, Accession #[FABP4], Gene ID: 2167, NCBI: NP_001433.1, UniProt: P15090
Catalog #MBS8503069
Price$310
Order / More InfoFABP4 Antibody from MYBIOSOURCE INC.
Product Specific References1. Tuncman, G. et al. (2006) Proc. Natl. Acad. Sci. USA 103, 6970-6975. 2. Haunerland, N.H. and Spener, F. (2004) Prog. Lipid Res. 43, 328-349. 3. Makowski, L. et al. (2001) Nat. Med. 7, 699-705. 4. Hotamisligil, G.S. et al. (1996) Science 274, 1377-1379.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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