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Antigenic Specificity | MXD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MXD1 Antibody detects endogenous levels of MXD1. Description: Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX.Post Translational Modifications: Ubiquitinated by BIRC2/c-IAP1, leading to its subsequent degradation by the proteasome.Subunit Structure: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with RNF17 (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human MXD1. |
Other Names | [MAD; MAD protein; MAD1; MAD1_HUMAN; MAX dimerization protein 1; Max dimerizer 1; Mxd1; Protein MAD] |
Gene, Accession # | [MXD1], Gene ID: 4084, NCBI: AAI43833.1, UniProt: Q05195 |
Catalog # | MBS9611416 |
Price | $240, $280 |
Order / More Info | MXD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |