PDCL3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDCL3
Clone[AT8F9]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionPDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as beta Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates.
ImmunogenImmunogen: Recombinant human PDCL3 (1-239aa) purified from E. coli
Other Names[Phosducin-Like protein 3; Phosducin-Like protein 3; HTPHLP; MGC3062; PHLP2A; PHLP3; VIAF; VIAF1], [PDCL3; PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A; PhLP2A; VIAF1; VIAF-1]
Gene, Accession #[PDCL3], Gene ID: 79031, NCBI: NP_076970, UniProt: Q9H2J4
Catalog #MBS200313
Price$240, $315
Order / More InfoPDCL3 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWilkinson J.C., et al. (2004) Biol. Chem. 279 (49):51091-51099; Hillier L.W., et al. (2005) Nature 434 (7034):724-731
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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