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Antigenic Specificity | PDCL3 |
Clone | [AT8F9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as beta Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates. |
Immunogen | Immunogen: Recombinant human PDCL3 (1-239aa) purified from E. coli |
Other Names | [Phosducin-Like protein 3; Phosducin-Like protein 3; HTPHLP; MGC3062; PHLP2A; PHLP3; VIAF; VIAF1], [PDCL3; PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A; PhLP2A; VIAF1; VIAF-1] |
Gene, Accession # | [PDCL3], Gene ID: 79031, NCBI: NP_076970, UniProt: Q9H2J4 |
Catalog # | MBS200313 |
Price | $240, $315 |
Order / More Info | PDCL3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wilkinson J.C., et al. (2004) Biol. Chem. 279 (49):51091-51099; Hillier L.W., et al. (2005) Nature 434 (7034):724-731 |