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Antigenic Specificity | ADAM15 (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ADAM15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 37-72 amino acids from the human region of human ADAM15. Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in |
Immunogen | n/a |
Other Names | [Disintegrin and metalloproteinase domain-containing protein 15; ADAM 15; 3424-; Metalloprotease RGD disintegrin protein; Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 15; MDC-15; Metargidin; ADAM15; MDC15] |
Gene, Accession # | [ADAM15], Gene ID: 8751, NCBI: NP_001248393.1, UniProt: Q13444 |
Catalog # | MBS9203549 |
Price | $165, $370 |
Order / More Info | ADAM15 (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kraetzschmar J.,et al.J. Biol. Chem. 271:4593-4596(1996). Herren B.,et al.FASEB J. 11:173-180(1997). Charrier L.,et al.Am. J. Physiol. 288:G346-G353(2005). Kleino I.,et al.BMC Mol. Biol. 8:90-90(2007). Zhong J.L.,et al.Mol. Cancer Res. 6:383-394(2008). |