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Antigenic Specificity | PDE6B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human PDE6B Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Other Names | [rd1; PDEB; RP40; CSNB3; CSNBAD2] |
Gene, Accession # | [PDE6B ], NCBI: JAO93243.1 |
Catalog # | MBS2536812 |
Price | $150, $225, $360 |
Order / More Info | PDE6B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |