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Antigenic Specificity | UBA7 (N-term), 239-268 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the N-terminal region of human UBA7. The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s,ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E1ubiquitin-activating enzyme family. The encoded enzyme is aretinoid target that triggers promyelocytic leukemia (PML)/retinoicacid receptor alpha (RARalpha) degradation and apoptosis in acutepromyeloc |
Immunogen | n/a |
Other Names | [Ubiquitin-like modifier-activating enzyme 7; Ubiquitin-activating enzyme 7; D8; Ubiquitin-activating enzyme E1 homolog; UBA7; UBE1L; UBE2] |
Gene, Accession # | [UBA7], Gene ID: 7318, NCBI: NP_003326.2, UniProt: P41226 |
Catalog # | MBS9211062 |
Price | $165, $370 |
Order / More Info | UBA7 (N-term), 239-268 Antibody from MYBIOSOURCE INC. |
Product Specific References | Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010) Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010) Feng, Q., et al. Mol. Cancer Ther. 7(12):3780-3788(2008) Durfee, L.A., et al. J. Biol. Chem. 283(35):23895-23902(2008) Takeuchi, T., et al. J. Biochem. 138(6):711-719(2005) |