PTP1B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPTP1B
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionTyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
ImmunogenImmunogen: A synthesized peptide derived from human PTP1B. Subcellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Interacts with EPHA3 at the cell membrane.
Other Names[Tyrosine-protein phosphatase non-receptor type 1; 3.1.3.48; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B], [PTPN1]
Gene, Accession #[PTP1B], Gene ID: 5770, NCBI: NP_001265547.1, UniProt: P18031
Catalog #MBS179391
Price$160, $340, $340
Order / More InfoPTP1B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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