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Antigenic Specificity | PTP1B |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. |
Immunogen | Immunogen: A synthesized peptide derived from human PTP1B. Subcellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Interacts with EPHA3 at the cell membrane. |
Other Names | [Tyrosine-protein phosphatase non-receptor type 1; 3.1.3.48; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B], [PTPN1] |
Gene, Accession # | [PTP1B], Gene ID: 5770, NCBI: NP_001265547.1, UniProt: P18031 |
Catalog # | MBS179391 |
Price | $160, $340, $340 |
Order / More Info | PTP1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |