TRIM2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRIM2
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionTRIM RING finger protein TRIM2, a ubiquitin ligase, is highly expressed in the nervous system. It binds to neurofilament light subunit (NF-L);and regulates NF-L ubiquitination. Deficiencies in TRIM2 increases NF-L level in axons and NF-L-filled axonal swellings in cerebellum, retina, spinal cord, and cerebral cortex. These deficiencies eventually lead to neurodegeneration, tremors and ataxia. It is proposed that TRIM2 has neuroprotection properties.
ImmunogenImmunogen: Peptide with sequence DSGNHCFKVYRYLQ, from the C Terminus of the TRIM2 protein sequence according to NP_056086.2; NP_001123539.1
Other Names[tripartite motif-containing protein 2 isoform 1; Tripartite motif-containing protein 2; tripartite motif-containing protein 2; tripartite motif containing 2; E3 ubiquitin-protein ligase TRIM2; RING finger protein 86], [TRIM2; TRIM2; CMT2R; RNF86; KIAA0517; RNF86]
Gene, Accession #[TRIM2], Gene ID: 23321, NCBI: NP_056086.2, UniProt: Q9C040
Catalog #MBS555931
Price$440
Order / More InfoTRIM2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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