Human VITAMIN D RECEPTOR Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human VITAMIN D RECEPTOR |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | dog (expected from sequence), mouse (expected from sequence), rat (expected from sequence) |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.5 mg/ml |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises human vitamin D nuclear hormone receptor (VDR) a 48 kDa member of the trans-acting transcriptional regulatory factors. On binding vitamin D, VDR regulates the expression of hormone sensitive genes. The main downstream target of VDR is involved in bone mineral metabolism although VDR is also involved in immune response and cancer metabolic pathways. VDR also acts as a receptor for secondary bile acid lithocholic acid. Additionally, signalling and oncogenic activity of beta-catenin signalling has been shown to be repressed by VDR. MBS221386 recognises human vitamin D nuclear hormone receptor (VDR) a 48 kDa member of the trans-acting transcriptional regulatory factors. On binding vitamin D, VDR regulates the expression of |
| Immunogen | Immunogen: Peptide sequence CGNQDYKYRVSD corresponding to the internal region of Vitamin D receptor (NP 000367.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antisera to human Vitamin D receptor were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [vitamin D3 receptor isoform VDRA; Vitamin D3 receptor; vitamin D3 receptor; 1,25-dihydroxyvitamin D3 receptor; nuclear receptor subfamily 1 group I member 1; protein phosphatase 1, regulatory subunit 163; vitamin D nuclear receptor variant 1; vitamin D (1,25- dihydroxyvitamin D3) receptor; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1], [VDR; VDR; NR1I1; PPP1R163; NR1I1; VDR] |
| Gene, Accession # | Gene ID: 7421, NCBI: NP_000367.1, UniProt: P11473 |
| Catalog # | MBS221386 |
| Price | $550 |
| Order / More Info | Human VITAMIN D RECEPTOR Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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