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Antigenic Specificity | DAPK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DAPK2 antibody detects endogenous levels of total DAPK2. Function: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polar |
Immunogen | Immunogen: A synthesized peptide derived from human DAPK2 Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in neutrophils and eosinophils (PubMed:24163421). Isoform 2 is expressed in embryonic stem cells (at protein level). Isoform 1 is ubiquitously expressed in all tissue types examined with high levels in heart, lung and skeletal muscle. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit Similarity: Pig (92%), Horse (100%), Sheep (92%), Rabbit (100%) |
Other Names | [DAK2; DAP kinase 2; DAP kinase related protein 1; DAP kinase related protein 1 beta isoform; DAP-kinase-related protein 1; DAPK2; DAPK2_HUMAN; Death associated protein kinase 2; Death-associated protein kinase 2; DRP 1; DRP-1; DRP1; MGC119312] |
Gene, Accession # | [DAPK2], Gene ID: 23604, NCBI: NP_055141.2, UniProt: Q9UIK4 |
Catalog # | MBS9608598 |
Price | $240, $280 |
Order / More Info | DAPK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |