Beta-2 Microglobulin (Renal Failure &Tumor Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBeta-2 Microglobulin (Renal Failure &Tumor Marker)
Clone[rB2M/961]
Host SpeciesMouse
Reactive Specieshuman and nonhuman primates.
IsotypeIgG2b, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alphaheavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alphaheavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alphaheavy chain form the peptide antigen-b
ImmunogenImmunogen: Recombinant Full length human B2M protein Cellular Localization: Cell Surface and Extracellular (Secreted)
Other Names[B2M; Beta 2 microglobin; Beta 2 microglobulin; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5.3; Hdcma22p]
Gene, Accession #[B2M], Gene ID: 567, NCBI: NP_004039.1, UniProt: P61769
Catalog #MBS4380187
Price$190, $340, $340
Order / More InfoBeta-2 Microglobulin (Renal Failure &Tumor Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesJosson, S., et al. 2011. ?2-Microglobulin induces epithelial to mesenchymal transition and confers cancer lethality and bone metastasis in human cancer cells. Cancer Res. 71: 2600-2610.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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