MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 |
| Clone | [MCAM/3046] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. |
| Immunogen | Immunogen: Recombinant human MCAM protein fragment (around aa226-374) (exact sequence is proprietary) |
| Other Names | [Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM); Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1] |
| Gene, Accession # | [MCAM], Gene ID: 4162, NCBI: P43121.2, UniProt: P43121 |
| Catalog # | MBS4381077 |
| Price | $190, $340, $340 |
| Order / More Info | MCAM (Melanoma Cell Adhesion Molecule)/MUC18/CD146 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Pruszak J et al. Stem Cells 25:2257-68 (2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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