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Antigenic Specificity | FBXW11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. This gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presen |
Immunogen | Immunogen: Rabbit polyclonal FBXW11(1) antibody was raised against a recombinate human FBXW11 protein 335-524aa (BC026213). |
Other Names | [Homo sapiens F-box and WD repeat domain containing 11, mRNA; F-box/WD repeat-containing protein 11; F-box/WD repeat-containing protein 11; F-box and WD repeats protein beta-TrCP2; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box protein Fbw1b; F-box/WD repeat-containing protein 1B; beta-transducin repeat-containing protein 2; homologous to Slimb protein; F-box and WD repeat domain containing 11; F-box and WD repeats protein beta-TrCP2; F-box/WD repeat-containing protein 1B; Homologous to Slimb protein; HOS], [FBXW11; FBXW11; Hos; BTRC2; FBW1B; Fbw11; BTRCP2; FBXW1B] |
Gene, Accession # | [FBXW11], Gene ID: 23291, NCBI: BC026213 |
Catalog # | MBS417509 |
Price | $230 |
Order / More Info | FBXW11 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Cui,W., Xiao,N., Xiao,H., et al. beta-TrCP-mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-kappaB activation. Mol. Cell. Biol. 32 (19), 3990-4000 (2012) |