CD34 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD34
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionCD34 is a type I transmembrane glycophosphoprotein expressed by hematopoietic stem/progenitor cells, vascular endothelium and some fibroblasts (1). CD34 expression has been the hallmark used to identify hematopoietic stem cells for many years. CD34+ hematopoietic stem cells expand and differentiate into all the lymphohematopoietic lineages upon cytokine or growth factor stimulation and lose CD34 expression upon differentiation. However, recent studies performed in various laboratories conflict with that convention (2). The extracellular domain of CD34 is homologous to CD43, a protein involved in cell-cell adhesion, and CD34 has been shown to function as a negative regulator of cell adhesion (3). CD34 associates with CrkL but not CrkII, is a
ImmunogenImmunogen: Recombinant protein of human CD34 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[Hematopoietic progenitor cell antigen CD34; CD34]
Gene, Accession #[CD34], Gene ID: 947, NCBI: NP_001020280.1, UniProt: P28906
Catalog #MBS8501439
Price$310
Order / More InfoCD34 Antibody from MYBIOSOURCE INC.
Product Specific References1. Felschow, D. M. et al. (2001) Blood 97, 3768-3775. 2. Sato, T. et al. (1999) Blood 94, 2548-2554. 3. Drew, E. et al. (2005) Immunity 22, 43-57. 4. Fackler, M. J. et al. (1992) J. Biol. Chem. 267, 17540-17546.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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