ABAT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityABAT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRabbit IgG polyclonal antibody for 4-aminobutyrate aminotransferase, mitochondrial(ABAT) detection. Background: 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. ABAT is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5- phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of humans ynapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenoty
ImmunogenImmunogen: E. coli-derived human ABAT recombinant protein (Position: K388-K500). Human ABAT shares 93.9% and 94.5% amino acid (aa) sequence identity with mouse and rat ABAT, respectively.
Other Names[ABAT; GABA aminotransferase; GABA AT; GABA T; GABA transaminase; GABA transferase; GABA-AT; GABA-T; GABAT; L AIBAT; L-AIBAT; LAIBAT; NPD009; P80404; 4-aminobutyrate aminotransferase, mitochondrial], [ABAT; ABAT; GABAT; NPD009; GABA-AT; GABAT; GABA-AT; GABA transaminase; GABA-T]
Gene, Accession #[ABAT], Gene ID: 18, NCBI: NP_000654.2, UniProt: P80404
Catalog #MBS178775
Price$280
Order / More InfoABAT Antibody from MYBIOSOURCE INC.
Product Specific References1. De Biase D, Barra D, Simmaco M, John RA, Bossa F (Jan 1995). Primary structure and tissue distribution of human 4-aminobutyrate aminotransferase. European Journal of Biochemistry / FEBS 227 (1-2): 476-80.2. Medina-Kauwe LK, Tobin AJ, De Meirleir L, Jaeken J, Jakobs C, Nyhan WL, Gibson KM (Jun 1999). 4-Aminobutyrate aminotransferase (GABA-transaminase) deficiency.Journal of Inherited Metabolic Disease 22 (4): 414-27.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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