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Antigenic Specificity | Brgl (SMARCA4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of SMARCA4 and does not cross-react with related proteins. UniPort Summary Function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREB |
Immunogen | Immunogen: Purified recombinant human SMARCA4 protein fragments expressed in E Coli. Cellular Localization: Nucleus |
Other Names | [BRG1; SNF2L4; BAF190; SNF2; SNF2LB; SWI2; hSNF2b; Mitotic growth and transcription activator; Protein brahma homolog 1; Protein BRG-1; BAF190A; ATP-dependent helicase SMARCA4; nuclear protein GRB1; FLJ39786; RTPS2; brahma protein-like 1; BRM/SWI2-related gene 1], [BRG1; SNF2; SWI2; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; SNF2-BETA] |
Gene, Accession # | [Brgl], Gene ID: 6597, NCBI: NP_001122316.1, UniProt: P51532 |
Catalog # | MBS857836 |
Price | $300 |
Order / More Info | Brgl (SMARCA4) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |