Brgl (SMARCA4) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBrgl (SMARCA4)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody detects endogenous levels of SMARCA4 and does not cross-react with related proteins. UniPort Summary Function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREB
ImmunogenImmunogen: Purified recombinant human SMARCA4 protein fragments expressed in E Coli. Cellular Localization: Nucleus
Other Names[BRG1; SNF2L4; BAF190; SNF2; SNF2LB; SWI2; hSNF2b; Mitotic growth and transcription activator; Protein brahma homolog 1; Protein BRG-1; BAF190A; ATP-dependent helicase SMARCA4; nuclear protein GRB1; FLJ39786; RTPS2; brahma protein-like 1; BRM/SWI2-related gene 1], [BRG1; SNF2; SWI2; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; SNF2-BETA]
Gene, Accession #[Brgl], Gene ID: 6597, NCBI: NP_001122316.1, UniProt: P51532
Catalog #MBS857836
Price$300
Order / More InfoBrgl (SMARCA4) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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