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Antigenic Specificity | TNFSF18 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total TNFSF18 polyclonal antibody. Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells.Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation. |
Immunogen | Immunogen: Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (72-199aa) |
Other Names | [Activation-inducible TNF-related ligand; AITRL; Glucocorticoid-induced TNF-related ligand; hGITRL; TNFSF18; AITRL; GITRL; TL6; UNQ149/PRO175] |
Gene, Accession # | [TNFSF18], Gene ID: 8995, NCBI: NP_005083.2, UniProt: Q9UNG2 |
Catalog # | MBS9416354 |
Price | $320 |
Order / More Info | TNFSF18 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |