CD11c Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD11c
Clone[ABM4C58]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein G purified
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionCD11c/CD18 (p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte matur
ImmunogenImmunogen Information: A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody.
Other Names[ITGAX; CD11C; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150, 95 alpha chain; Leukocyte adhesion receptor p150, 95; to CD11c; CD11c; CD11c], [ITGAX; ITGAX; CD11C; SLEB6; CD11C]
Gene, Accession #[CD11c], Gene ID: 3687, NCBI: P20702.3, UniProt: P20702
Catalog #MBS668290
Price$145, $255
Order / More InfoCD11c Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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