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Antigenic Specificity | CD11c |
Clone | [ABM4C58] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein G purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11c/CD18 (p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte matur |
Immunogen | Immunogen Information: A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody. |
Other Names | [ITGAX; CD11C; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150, 95 alpha chain; Leukocyte adhesion receptor p150, 95; to CD11c; CD11c; CD11c], [ITGAX; ITGAX; CD11C; SLEB6; CD11C] |
Gene, Accession # | [CD11c], Gene ID: 3687, NCBI: P20702.3, UniProt: P20702 |
Catalog # | MBS668290 |
Price | $145, $255 |
Order / More Info | CD11c Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |