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Antigenic Specificity | CYP2C8 (N-term), 74-105 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYP2C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-105 amino acids from the N-terminal region of human CYP2C8. CYP2C8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. |
Immunogen | n/a |
Other Names | [Cytochrome P450 2C8; CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylase; CYP2C8] |
Gene, Accession # | [CYP2C8], Gene ID: 1558, NCBI: NP_000761.3, UniProt: P10632 |
Catalog # | MBS9204446 |
Price | $165, $370 |
Order / More Info | CYP2C8 (N-term), 74-105 Antibody from MYBIOSOURCE INC. |
Product Specific References | Adjei,G.O., Antimicrob. Agents Chemother. 52 (12), 4400-4406 (2008) Aquilante,C.L., Hum. Genomics 3 (1), 7-16 (2008) Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004) |