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Antigenic Specificity | TRIM28 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of TRIM28 are known to exist; this antibody will detect all three isoforms. TRIM28 Antibody: TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation. |
Immunogen | Immunogen: Rabbit polyclonal TRIM28 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TRIM28. Buffer: TRIM28 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TRIM28; KAP1; TF1B; RNF96; TIF1B; KAP1; Transcription intermediary factor 1-beta; E3 SUMO-protein ligase TRIM28; TIF1-beta; tripartite motif containing 28], [TRIM28; TRIM28; KAP1; TF1B; RNF96; TIF1B; PPP1R157; KAP1; RNF96; TIF1B; TIF1-beta; KAP-1; KRIP-1] |
Gene, Accession # | [TRIM28], Gene ID: 10155, NCBI: NP_005753, UniProt: Q13263 |
Catalog # | MBS153669 |
Price | $375 |
Order / More Info | TRIM28 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |