TNFA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total TNFA protein. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.Neville M.J., J. Immunol. 162:4745-4754(1999).Xie T., Genome Res. 13:2621-2636(2003).Kim Y.J., Hum. Mol. Genet. 12:2541-2546(2003).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TNFA.
Other Names[Protein name Tumor necrosis factor [Precursor]; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin]
Gene, Accession #[TNFA], Gene ID: 7124, NCBI: NP_000585.2, UniProt: P01375
Catalog #MBS9400677
Price$200, $255
Order / More InfoTNFA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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