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Antigenic Specificity | Phospho-FOS (T232) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FOS Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T232 of human FOS. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
Immunogen | n/a |
Other Names | [Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7; FOS; G0S7] |
Gene, Accession # | [FOS], Gene ID: 2353, NCBI: NP_005243.1, UniProt: P01100 |
Catalog # | MBS9210743 |
Price | $165, $370 |
Order / More Info | Phospho-FOS (T232) Antibody from MYBIOSOURCE INC. |
Product Specific References | Gensch, E., et al., J. Biol. Chem. 279(37):39085-39093 (2004). Myllykangas, S., et al., Genes Chromosomes Cancer 40(4):334-341 (2004). Wu, M.Y., et al., World J. Gastroenterol. 10(4):476-480 (2004). Monje, P., et al., Mol. Cell. Biol. 23(19):7030-7043 (2003). Lavezzi, A.M., et al., Pathol. Int. 53(11):769-774 (2003). |