SMAC/Diablo Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SMAC/Diablo |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat, mouse, human |
| Isotype | n/a |
| Format | serum |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Smac/DIABLO (second mitochondrial-derived activator of caspase/direct IAP binding protein with low pI) is encoded by the nucleus and resides as a precursor within the intermembranous space of the mitochondria. During apoptosis, Smac/DIABLO is proteolytically cleaved and released from the mitochondria into the cytosol, where it promotes cell death by interacting with IAPs and inhibiting their anti-apoptotic function. In turn, certain IAPs may degrade Smac/DIABLO and block its cell death function. Smac/DIABLO is expressed in a wide range of normal tissues and some tumor cells lines, and its over-expression in tumor cell lines can trigger both extrinsic and intrinsic apoptosis pathways. |
| Immunogen | Immunogen Information: A full-length recombinant protein of human SMAC was used as immunogen for this antibody |
| Other Names | [DIABLO; SMAC; Direct IAP-binding protein with low pI; Smac; Second mitochondria-derived activator of caspase; to SMAC/Diablo; SMAC/Diablo; SMAC/Diablo], [DIABLO; DIABLO; SMAC; DFNA64; SMAC; Smac] |
| Gene, Accession # | [DIABLO], Gene ID: 56616, NCBI: Q9NR28.1, UniProt: Q9NR28 |
| Catalog # | MBS668782 |
| Price | $270 |
| Order / More Info | SMAC/Diablo Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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