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Antigenic Specificity | Mouse CD11b |
Clone | [5C6] |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 1 mg |
Concentration | IgG concentration 1 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CD11b antibody, clone 5C6 recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. MBS216530 immunoprecipitates a heterodimer of 165 and 95kD. Rat anti Mouse CD11b antibody, clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes. |
Immunogen | n/a |
Other Names | [Integrin alpha-M; Integrin alpha-M; integrin alpha-M; CD11 antigen-like family member B; CD11B (p170); CR-3 alpha chain; Mac-1 alpha; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; leukocyte adhesion receptor MO1; macrophage antigen alpha; integrin alpha M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; CD_antigen: CD11b], [Itgam; Itgam; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik] |
Gene, Accession # | [CD11b], Gene ID: 16409, NCBI: P05555.2, UniProt: P05555 |
Catalog # | MBS216530 |
Price | $750 |
Order / More Info | Mouse CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |