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Antigenic Specificity | TLR8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 13 amino acid peptide near the amino terminus of human TLR8. |
Other Names | [Toll-like receptor 8] |
Gene, Accession # | [TLR8], Gene ID: 51311, NCBI: NP_619542 |
Catalog # | MBS9411370 |
Price | $320 |
Order / More Info | TLR8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |