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Antigenic Specificity | Interleukine 10 (IL-10) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1.kappa |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
Immunogen | Immunogen: Ni-NTA purified recombinant human IL-10 expressed in E Coli strain BL21 (DE3). |
Other Names | [IL-10; IL-10], [SPPV_03] |
Gene, Accession # | [IL-10], Gene ID: 944684, NCBI: NP_659579.1 |
Catalog # | MBS418394 |
Price | $445 |
Order / More Info | Interleukine 10 (IL-10) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Vieira P, et al. PNAS, 1991.88:1172-1176 |