PEN2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PEN2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PEN2 Antibody: PEN2, in addition to presenilin, nicastrin, and APH-1 forms the gamma-secretase protein complex, a membrane-bound aspartyl protease that can cleave certain proteins at peptide bonds buried within the hydrophobic environment of the lipid bilayer. This cleavage is responsible for a key step in signaling from several cell-surface receptors and is thought to be required for the generation of the neurotoxic amyloid peptides that are central to the pathogenesis of Alzheimer's disease. Like the tumor necrosis factor-alpha-converting enzyme (TACE) and the beta-site cleavage enzyme (BACE) protease families, gamma-secretase will cleave the amyloid precursor protein (APP), but within the intramembrane region of APP, resulting in either |
| Immunogen | Immunogen: PEN2 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human PEN2. Buffer: PEN2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [PEN2; PEN2; PEN-2; MDS033; MSTP064; PEN2; Gamma-secretase subunit PEN-2; Presenilin enhancer protein 2; presenilin enhancer 2 homolog (C. elegans)], [PSENEN; PSENEN; PEN2; PEN-2; MDS033; MSTP064; PEN2] |
| Gene, Accession # | [PSENEN], Gene ID: 55851, NCBI: NP_758844, UniProt: Q9NZ42 |
| Catalog # | MBS150886 |
| Price | $375 |
| Order / More Info | PEN2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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