PRKAR1A Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PRKAR1A antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PRKAR1A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The second messenger cyclic AMP (cAMP) activates cAMP-dependent protein kinase (PKA or cAPK) in mammalian cells and controls many cellular mechanisms such as gene transcription, ion transport, and protein phosphorylation (1). Inactive PKA is a heterotetramer composed of a regulatory subunit (R) dimer and a catalytic subunit (C) dimer. In this inactive state, the pseudosubstrate sequences on the R subunits block the active sites on the C subunits. Three C subunit isoforms (C-alpha, C-beta, and C-gamma) and two families of regulatory subunits (RI and RII) with distinct cAMP binding properties have been identified. The two R families exist in two isoforms, alpha and beta (RI-alpha, RI-beta, RII-alpha, and RII-beta). Upon binding of cAMP to the |
| Immunogen | Immunogen: Recombinant protein of human PRKAR1A Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [PRKAR1A; CAR; CNC; CNC1; DKFZp779L0468; MGC17251; PKR1; PPNAD1; PRKAR1; TSE1] |
| Gene, Accession # | [PRKAR1A], Gene ID: 5573, NCBI: NP_001263218.1, UniProt: P10644 |
| Catalog # | MBS8502807 |
| Price | $310 |
| Order / More Info | PRKAR1A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Montminy, M. (1997) Annu. Rev. Biochem. 66, 807-822. 2. Dell'Acqua, M.L. and Scott, J.D. (1997) J. Biol. Chem. 272, 12881-12884. 3. Tan, Y. et al. (2000) J. Biol. Chem. 275, 25865-25869. 4. Gonzalez, G.A. and Montminy, M.R. (1989) Cell 59, 675-680. 5. Fang, X. et al. (2000) Proc. Natl. Acad. Sci. USA 97, 11960-11965. 6. Dumaz, N. and Marais, R. (2003) J. Biol. Chem. 278, 29819-29823. 7. Moore, M.J. et al. (2002) J. Biol. Chem. 277, 47878-47884. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.