Edit |   |
---|---|
Antigenic Specificity | MAGED1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed. |
Immunogen | Immunogen: Recombinant human Melanoma-associated antigen D1 protein (C-200AA) |
Other Names | [Melanoma-associated antigen D1; MAGE tumor antigen CCF; MAGE-D1 antigen; Neurotrophin receptor-interacting MAGE homolog; MAGED1; NRAGE; PP2250; PRO2292] |
Gene, Accession # | [MAGED1], Gene ID: 9500, NCBI: NP_001005332.1, UniProt: Q9Y5V3 |
Catalog # | MBS7043750 |
Price | $120, $160 |
Order / More Info | MAGED1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |