DNJC2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDNJC2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThe antibody detects endogenous levels of DNJC2 protein. Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at Lys-119 (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilita
ImmunogenImmunogen: Synthesized peptide derived from part region of human DNJC2 protein
Other Names[Rabbit DNJC2; DnaJ homolog subfamily C member 2; M-phase phosphoprotein 11; Zuotin-related factor 1]
Gene, Accession #[DNJC2], Gene ID: 27000, NCBI: Q99543.4, UniProt: Q99543
Catalog #MBS9708982
Price$130, $220, $325
Order / More InfoDNJC2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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