Filamin A/FLNA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFilamin A/FLNA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Filamin A/FLNA detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human; Mouse; Rat.Background: Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene. It is mapped to Xq28. The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodu
ImmunogenImmunogen: E. coli-derived human Filamin A/FLNA recombinant protein (Position: E451-Q638).
Other Names[Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin; FLNA; FLN, FLN1]
Gene, Accession #[FLNA], Gene ID: 2316, NCBI: NP_001104026.1, UniProt: P21333
Catalog #MBS1752833
Price$315
Order / More InfoFilamin A/FLNA Antibody from MYBIOSOURCE INC.
Product Specific References1. Gorlin JB, Henske E, Warren ST, Kunst CB, D'Urso M, Palmieri G, Hartwig JH, Bruns G, Kwiatkowski DJ (October 1993). Actin-binding protein (ABP-280) filamin gene (FLN) maps telomeric to the color vision locus (R/GCP) and centromeric to G6PD in Xq28. Genomics. 17 (2): 496-8. 2. Robertson SP, Twigg SR, Sutherland-Smith AJ, Biancalana V, Gorlin RJ, Horn D, Kenwrick SJ, Kim CA, Morava E, Newbury-Ecob R, Orstavik KH, Quarrell OW, Schwartz CE, Shears DJ, Suri M, Kendrick-Jones J, Wilkie AO (March 2003). Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans. Nat Genet. 33 (4): 487-91. 3. Graber P, Witt HT (February 1976). Relations between the electrical potential, pH gradient, proton flux and phosphorylation in the photosynthetic membrane. Biochimica et Biophysica Acta. 423 (2): 141-63.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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