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Antigenic Specificity | Snaclec rhodocytin subunit alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Calloselasma Rhodostoma |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. |
Immunogen | Immunogen: Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA) |
Other Names | [Snaclec rhodocytin subunit alpha] |
Gene, Accession # | NCBI: Q9I841.1, UniProt: Q9I841 |
Catalog # | MBS7104053 |
Price | $160, $235 |
Order / More Info | Snaclec rhodocytin subunit alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |