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Antigenic Specificity | Human Complement C3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Acylation stimulating protein (ASP): adipogenic hormone that stimulates |
Immunogen | Immunogen: Recombinant human Complement C3 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31300 / sc-17237 / sc-14612 / sc-14613 / sc-31299 / sc-20137 |
Other Names | [C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; CPAMD1], [C3; C3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; CPAMD1; C3bc; ASP] |
Gene, Accession # | [C3], Gene ID: 718, NCBI: NP_000055.2, UniProt: P01024 |
Catalog # | MBS1488274 |
Price | $160, $235 |
Order / More Info | Human Complement C3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |