Synuclein-alpha (Phospho Tyr125) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySynuclein-alpha (Phospho Tyr125)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-Synuclein-alpha (Y125) Polyclonal Antibody detects endogenous levels of Synuclein-alpha protein only when phosphorylated at Y125. Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for SNCA.
ImmunogenImmunogen: Synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Y125
Other Names[Rabbit Synuclein-alpha (phospho Tyr125); NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP]
Gene, Accession #[SNCA], Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840
Catalog #MBS9701268
Price$130, $220, $325
Order / More InfoSynuclein-alpha (Phospho Tyr125) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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