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Antigenic Specificity | Synuclein-alpha (Phospho Tyr125) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Synuclein-alpha (Y125) Polyclonal Antibody detects endogenous levels of Synuclein-alpha protein only when phosphorylated at Y125. Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for SNCA. |
Immunogen | Immunogen: Synthesized peptide derived from human Synuclein-alpha around the phosphorylation site of Y125 |
Other Names | [Rabbit Synuclein-alpha (phospho Tyr125); NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP] |
Gene, Accession # | [SNCA], Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840 |
Catalog # | MBS9701268 |
Price | $130, $220, $325 |
Order / More Info | Synuclein-alpha (Phospho Tyr125) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |