Edit |   |
Antigenic Specificity | TNIP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNIP3 antibody detects endogenous levels of total TNIP3. Function: Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.Subunit Structure: Interacts with TNFAIP3. Interacts with polyubiquitin. |
Immunogen | Immunogen: A synthesized peptide derived from human TNIP3 Subcellular Location: Cytoplasmic and Nuclear (based on other ABIN family members). Tissue Specificity: Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyro |
Other Names | [A20 binding inhibitor of NF kappa B activation 3; ABIN 3; ABIN 3 beta; FLJ21162; LIND; Listeria induced; Listeria induced gene protein; TNFAIP3 interacting protein 3; TNFAIP3 interacting protein 3 beta; TNIP3; TNIP3 beta] |
Gene, Accession # | [TNIP3], Gene ID: 79931, NCBI: NP_001122315.2, UniProt: Q96KP6 |
Catalog # | MBS9609400 |
Price | $240, $280 |
Order / More Info | TNIP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |