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Antigenic Specificity | Bax |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bax Polyclonal Antibody detects endogenous levels of Bax protein. The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated ap |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Bax at AA range: 10-90 |
Other Names | [Rabbit Bax] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_004315.1, UniProt: Q07815 |
Catalog # | MBS9706576 |
Price | $130, $220, $325 |
Order / More Info | Bax Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |