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Antigenic Specificity | CX3CL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 18 amino acids near the amino terminus of human CX3CL1. |
Other Names | [CX3C, CX3C membrane-anchored chemokine, neurotactin, small] |
Gene, Accession # | [CX3CL1], Gene ID: 6376, NCBI: AAB50014 |
Catalog # | MBS9409826 |
Price | $320 |
Order / More Info | CX3CL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |