HTRA2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHTRA2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti HtrA2 antibody recognizes protein serine protease HtrA2, also known as OMI and PRSS25. HtrA2 is a member of the HtrA serine protease family (Gray et al. 2000) and was identified as a mammalian homologue of the Escherishia coli protein HtrA (Faccio et al. 2000). HtrA2 forms a homotrimer which is important for its function and serine protease activity (Li et al. 2002). HtrA2 is released from mitochondria and interacts with X chromosome-linked inhibitor of apoptosis (XIAP) (Suzuki et al. 2001). The XIAP binding through a reaper-like motif is required for induction of apoptosis (Martins et al. 2002). HtrA2 is upregulated in hepatocellular carcinoma (Wang et al. 2018) and has been associated with chemosentistivity in various cancers
ImmunogenImmunogen: Recombinant human HtrA2
Other Names[HTRA2], [HTRA2; HTRA2; OMI; MGCA8; PARK13; PRSS25; OMI; PRSS25; HtrA2]
Gene, Accession #[HTRA2], Gene ID: 27429, NCBI: NP_037379.1, UniProt: O43464
Catalog #MBS225581
Price$375
Order / More InfoHTRA2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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