ITBP1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ITBP1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ITBP1 antibody detects endogenous levels of total ITBP1. Function: Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stimulates cellular proliferation in a fibronectin-dependent manner. Involved in the regulation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in endothelial cells and fibroblasts (at protein level). Ubiquitously expressed. Expressed in intestine, colon, testis, ovary, thymus, spleen and prostate. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (83%), Horse (100%), Sheep (92%), Rabbit (92%), Dog (100%) |
| Other Names | [Bodenin; DKFZp686K08158; ICAP 1; ICAP 1A; ICAP 1alpha; ICAP 1B; ICAP-1; ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B; Integrin beta 1 binding protein 1; Integrin beta-1-binding protein 1; Integrin cytoplasmic domain associated protein 1 alpha; Integrin cytoplasmic domain associated protein 1; Integrin cytoplasmic domain associated protein 1 beta; Integrin cytoplasmic domain-associated protein 1; ITBP1_HUMAN; ITGB1BP1] |
| Gene, Accession # | [ITBP1], Gene ID: 9270, NCBI: NP_001305995.1, UniProt: O14713 |
| Catalog # | MBS9604060 |
| Price | $240, $280 |
| Order / More Info | ITBP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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