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Antigenic Specificity | TNF-R1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNF-R1 Polyclonal Antibody detects endogenous levels of TNF-R1 protein. The protein encoded by TNFRSF1A (TNF receptor superfamily member 1A) is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever s |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human TNF-R1 at AA range: 350-430 |
Other Names | [Rabbit TNF-R1; TNFRSF1A; TNFAR; TNFR1; Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD antigen CD120a] |
Gene, Accession # | [TNF-R1], Gene ID: 7132, NCBI: NP_001056.1, UniProt: P19438 |
Catalog # | MBS9707029 |
Price | $130, $220, $325 |
Order / More Info | TNF-R1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |