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Antigenic Specificity | HEF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.93 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HEF1 protein. Cas-L a widely expressed docking protein which plays a central coordinating role for tyrosine-kinase-based signaling in cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form. Phosphorylated following integrin beta-1, antigen receptor, or C1a calcitonin receptor signaling. Transformation of fibroblasts with v-ABL results in an increase in its tyrosine phosphorylation. Phosphorylated by fo |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment contain a sequence corresponding to a region within amino acids 115 and 444 of HEF1. |
Other Names | [CAS-L; CAS2; CASL; CASS2; HEF1; dJ49G10.2; dJ761I2.1; NEDD9; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)); renal carcinoma antigen NY-REN-12; Crk-associated substr] |
Gene, Accession # | [HEF1], Gene ID: 4739, NCBI: NP_001135865.1, UniProt: Q14511 |
Catalog # | MBS9409637 |
Price | $320 |
Order / More Info | HEF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |