HEF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHEF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.93 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total HEF1 protein. Cas-L a widely expressed docking protein which plays a central coordinating role for tyrosine-kinase-based signaling in cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form. Phosphorylated following integrin beta-1, antigen receptor, or C1a calcitonin receptor signaling. Transformation of fibroblasts with v-ABL results in an increase in its tyrosine phosphorylation. Phosphorylated by fo
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment contain a sequence corresponding to a region within amino acids 115 and 444 of HEF1.
Other Names[CAS-L; CAS2; CASL; CASS2; HEF1; dJ49G10.2; dJ761I2.1; NEDD9; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)); renal carcinoma antigen NY-REN-12; Crk-associated substr]
Gene, Accession #[HEF1], Gene ID: 4739, NCBI: NP_001135865.1, UniProt: Q14511
Catalog #MBS9409637
Price$320
Order / More InfoHEF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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