CD31 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD31
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionCD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells and endothelial cells, and modulates cell adhesion, endothelial cell migration and angiogenesis (1). CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical stress or oxidative stress), presumably by Src family members (2). The tyrosine phosphorylation mediates associations with a number of SH2 domain containing binding partners such as PI3-kinase, SHIP, PLC gamma and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules (3).
ImmunogenImmunogen: A synthetic peptide of human CD31 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[PECAM1; CD31; FLJ58394; PECAM-1]
Gene, Accession #[CD31], Gene ID: 5175, NCBI: NP_000433.4, UniProt: P16284
Catalog #MBS8504068
Price$310
Order / More InfoCD31 Antibody from MYBIOSOURCE INC.
Product Specific References1. Newman, P.J. (1997) J. Clin. Invest. 99, 3-8. 2. Cao, M. Y. et al. (1998) J. Biol. Chem. 273, 15765-15772. 3. Ilan, N. and Madri, J.A. (2003) Curr. Opin. Cell Biol. 15, 515-524.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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