TNF-alpha, Human Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TNF-alpha, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | TNF-alpha, Human |
| Clone | 52B83 |
| Host Species | Mouse |
| Reactive Species | reactivity: human. cross reactivity: guinea pig, mouse, rhesus monkey |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), P, Western Blot (WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 52B83 reacts with tumor necrosis factor alpha (TNF-alpha). TNF-alpha is a homotrimeric 17 kDa protein, that interacts with either one of the two types of TNF-receptors, termed I and II, leading to receptor cross-linking and signal transduction. The receptors differ strongly in their intra-cellular signaling pathways. TNF-alpha was originally described as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Furthermore,- TNF-alpha is found to be a central mediator in many inflammatory and immunological processes. It can be induced by various products of micro-organisms and by various cytokines leading to expression |
| Immunogen | n/a |
| Other Names | [TNF, TNF-SF2, DIF, Cachectin], [TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
| Gene, Accession # | [TNF-alpha], Gene ID: 7124, NCBI: CAA26669.1, UniProt: P01375 |
| Catalog # | MBS584012 |
| Price | $470 |
| Order / More Info | TNF-alpha, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bradding, P et al; Interleukin-4, -5, and -6 and Tumor Necrosis Factor-alpha in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994, 10: 471 2. Bradding, P et al: TNFalpha is localized to nasal mucosal mast cells and is released in acute allergic rhinitis. Clin Exp Allergy 1995, 25: 406 3. Gerspach, J et al; Detection of membrane-bound Tumor Necrosis Factor (TNF): an analysis of TNF-specific reagents. Microsc Res Tech 2000, 50: 243 4. Laan van der, N et al; Tumor necrosis factor alpha (TNFalpha) in human skin: a comparison of different antibodies for immunohistochemistry. Arch Dermatol Res 2001, 293: 226 5. Lee, E et al; Clinical and immunohistochemical characteristics of mucoceles. Ann Dermatol 2009, 21:345 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies