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Antigenic Specificity | ATG4C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATG4C antibody is human, mouse and rat reactive. ATG4C is predicted to not cross-react with other ATG4 proteins. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4C, also known as autophagin-3, is one of four mammalian orthologs of the yeast ATG4 protein; all four are cysteine proteases (3). Recent studies have shown that ATG4C and Beclin-1 are regulated by the microRNA miR-376b; overexpression of miR-376b led to decreased mRNA and protein levels, |
Immunogen | Immunogen: ATG4C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ATG4C. Buffer: ATG4C antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ATG4C; APG4C; AUTL1; AUTL3; APG4-C; APG4C; Cysteine protease ATG4C; AUT-like 3 cysteine endopeptidase; autophagy related 4C, cysteine peptidase], [ATG4C; ATG4C; APG4C; AUTL1; AUTL3; APG4-C; APG4C; AUTL1; AUTL3] |
Gene, Accession # | [ATG4C], Gene ID: 84938, NCBI: NP_835739, UniProt: Q96DT6 |
Catalog # | MBS153609 |
Price | $375 |
Order / More Info | ATG4C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |