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Antigenic Specificity | BRD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal antibody to detect BRD4 in human mouse and rat samples. Background: The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as readers of histone acetylation marks regulating the transcription of target promoters. The BET family of proteins, defined by tandem Bromodomain |
Immunogen | Immunogen: Synthetic peptide near the C-terminal. Positive Control: Western blot: Rat kidney lysate |
Other Names | [Bromodomain containing 4; isoform CRA_b; HUNK1], [BRD4; BRD4; CAP; MCAP; HUNK1; HUNKI; HUNK1] |
Gene, Accession # | [BRD4], Gene ID: 23476, NCBI: NP_055114.1, UniProt: O60885 |
Catalog # | MBS840558 |
Price | $150, $325 |
Order / More Info | BRD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |