HIRA (N-term), 32-61 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHIRA (N-term), 32-61
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis HIRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human HIRA. This gene encodes a histone chaperone that preferentiallyplaces the variant histone H3.3 in nucleosomes. Orthologs of thisgene in yeast, flies, and plants are necessary for the formation oftranscriptionally silent heterochomatin. This gene plays animportant role in the formation of the senescence-associatedheterochromatin foci. These foci likely mediate the irreversiblecell cycle changes that occur in senescent cells. It is consideredthe primary candidate gene in some haploinsufficiency syndromessuch as DiGeorge syndrome, and insufficient production
Immunogenn/a
Other Names[Protein HIRA; TUP1-like enhancer of split protein 1; HIRA; DGCR1; HIR; TUPLE1]
Gene, Accession #[HIRA], Gene ID: 7290, NCBI: NP_003316.3, UniProt: P54198
Catalog #MBS9211903
Price$165, $370
Order / More InfoHIRA (N-term), 32-61 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBailey, S.D., et al. Diabetes Care (2010) In press : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Banumathy, G., et al. Mol. Cell. Biol. 29(3):758-770(2009) Ramelli, G.P., et al. Dev Med Child Neurol 50(12):953-955(2008) Zhang, R., et al. Mol. Cell. Biol. 27(6):2343-2358(2007)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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