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Antigenic Specificity | CNOT10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CNOT10 antibody detects endogenous levels of CNOT10. Function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.Subunit Structure: Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaff |
Immunogen | Immunogen: A synthesized peptide derived from human CNOT10. Subcellular Location: Nucleus Predicted Cross Reactivity: Horse, Rabbit, Dog, Chicken Similarity: Horse (100%), Rabbit (83%), Dog (100%), Chicken (91%) |
Other Names | [CCR4 NOT transcription complex subunit 10; CCR4-NOT transcription complex subunit 10; CNOT 10; CNOT10; CNOTA_HUMAN; DKFZp434K115; FLJ12890; FLJ13165] |
Gene, Accession # | [CNOT10], Gene ID: 25904, NCBI: NP_001243670.1, UniProt: Q9H9A5 |
Catalog # | MBS9603594 |
Price | $240, $280 |
Order / More Info | CNOT10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |