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Antigenic Specificity | CHD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CHD5 antibody detects endogenous levels of total CHD5. Function: Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at 'Lys-27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes ma |
Immunogen | Immunogen: A synthesized peptide derived from human CHD5 Subcellular Location: Nucleus. Tissue Specificity: Preferentially expressed in total brain, fetal brain, and cerebellum. It is also moderately expressed in the adrenal gland and detected in testis. |
Other Names | [ATP-dependent helicase CHD5; CHD 5; CHD-5; CHD5; CHD5_HUMAN; Chromodomain-helicase-DNA-binding protein 5; DKFZp434N231; KIAA0444; RP1-233K16.2] |
Gene, Accession # | [CHD5], Gene ID: 26038, NCBI: NP_056372.1, UniProt: Q8TDI0 |
Catalog # | MBS9608748 |
Price | $240, $280 |
Order / More Info | CHD5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |