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Antigenic Specificity | ENG (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ENG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-318 amino acids from the Central region of human ENG. Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. |
Immunogen | n/a |
Other Names | [Endoglin; CD105; ENG; END] |
Gene, Accession # | [ENG], Gene ID: 2022, NCBI: NP_000109.1, UniProt: P17813 |
Catalog # | MBS9203353 |
Price | $165, $370 |
Order / More Info | ENG (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Bellon T.,et al.Eur. J. Immunol. 23:2340-2345(1993). Humphray S.J.,et al.Nature 429:369-374(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Gougos A.,et al.J. Biol. Chem. 265:8361-8364(1990). McAllister K.A.,et al.Nat. Genet. 8:345-351(1994). |