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Antigenic Specificity | IL17A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF -kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression oflL6 and cyclooxygenase-2 (pTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In pso |
Immunogen | Immunogen: Fusion protein of IL17 Calculated Molecular Weight: 155aa; 18kDa Observed Molecular Weight: 32-35kDa |
Other Names | [CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A,interleukin 17A] |
Gene, Accession # | [IL17A], Gene ID: 3605, NCBI: Q16552, UniProt: BC067505 |
Catalog # | MBS2523519 |
Price | $195, $270, $435 |
Order / More Info | IL17A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |